Abstract

The paper documents the major difficulties observed in the oral language development of individuals with mental retardation of genetic origin. The extent of inter- and within-syndrome variability is evaluated. More specifically, a comparative analysis of typical language phenotypes in several genetic syndromes is attempted and the possible brain underpinnings of the observed differences are envisaged. Recent cases of favorable language development in individuals with mental retardation are summarized and explanatory variables are discussed.

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