Abstract

Abstract: Cancer poses a significant threat to human life and well-being, resulting in numerous individuals suffering and succumbing to various forms of the disease each year. Considerable resources have been allocated to combat cancer, yet the limitations of existing anticancer agents, including their side effects and the development of drug resistance, have left substantial challenges in our quest to conquer cancer. Thus, there is an urgent necessity to discover and develop novel chemical compounds with the potential to inhibit cancer growth. In this review, we primarily focus on examining the effectiveness of two distinct classes of carbazole-based compounds: carboline derivatives and diazacarbazole derivatives. Diazacarbazole derivatives, a relatively unexplored area, hold promise for offering a fresh perspective and valuable opportunities to overcome the formidable obstacles in the ongoing battle against cancer. Additionally, we present several synthetic methods for creating the essential structural frameworks of carbazole-based tricyclic compounds.

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