Abstract

Cobalt nanoparticles (CoNPs) are promising nanomaterials with exceptional catalytic magnetic, electronic, and chemical properties. The nano size and developed surface open a wide range of applications of cobalt nanoparticles in biomedicine along with those properties. The present review assessed the current environmentally friendly synthesis methods used to synthesize CoNPs with various properties, such as size, zeta potential, surface area, and magnetic properties. We systematized several methods and provided some examples to illustrate the synthetic process of CoNPs, along with the properties, the chemical formula of obtained CoNPs, and their method of analysis. In addition, we also looked at the potential application of CoNPs from water purification cytostatic agents against cancer to theranostic and diagnostic agents. Moreover, CoNPs also can be used as contrast agents in magnetic resonance imaging and photoacoustic methods. This review features a comprehensive understanding of the synthesis methods and applications of CoNPs, which will help guide future studies on CoNPs.

Highlights

  • The rate of hydrogen formation when using this catalyst was 1807 mL·g−1 cat·min−1, the stability of the catalyst is relatively low after the fifth hydrolysis cycle, and the catalyst efficiency dropped to 32.5%, which they attributed to the fact that borate particles are adsorbed on the catalyst surface after the first cycle, which can change the electronic configuration of cobalt and reduces its catalytic activity

  • This review mainly focuses on the latest advances in synthesizing, modifying, and applying cobalt nanoparticles in catalysis, cancer treatment, and diagnostic materials based on Cobalt nanoparticles (CoNPs)

  • Particular attention should be paid to using cobalt nanoparticles as a contrast agent in MRI and photoacoustic tomography, improving the comprehensive study of body tissues and diagnosing diseases with high accuracy

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Summary

Introduction

There has been a tendency towards developing and applying new materials with new properties [1,2], with particular attention paid to nanomaterials and nanoparticles [3,4,5] due to their several unique properties, which make them applicable in various fields—from microelectronics to biomedicine [6,7,8]. Of 26 It shou be noted that due to their physico-chemical properties and small size, cobalt nanop can be successfully used as sensors to determine various substances [25]. Cobalt nanoparticles can beof used for energycobalt storage,nanoparticles as catalysts, in medicine, in microDue to the simplicity obtaining and their high applie electronics, as contrast agents, and as a basis for drug delivery systems [19,20,21,22]. Catalysis toalso thebemain for using nanoparticles as a carrier targeted drug delivery It should notedbiomed plications of cobalt nanoparticles, suchand as anticancer therapy and diagnostic that due to their physico-chemical properties small size, cobalt nanoparticles can be mate successfully used as sensors to determine various substances [25]

Synthesis
Method of isCoNPs
Electrochemical Method
Hydrothermal Method of CoNPs Synthesis
The Solvothermal Method of CoNPs Synthesis
Microemulsion Method of CoNPs Synthesis
Green Methods of CoNPs Synthesis
Physical Methods of CoNPs Synthesis
Vapor Condensation Method
The Arc Plasma-Assisted Deposition Method
Liquid-Phase Plasma Method
The Ultrasonic Method
Preparation of Hybrid Materials Based on CoNPs
CoNPs in Catalysis
CoNPs as an Anticancer Drug
CoNPs as a Contrast
Magnetic Applications of CoNPs
CoNPs Toxicity
Findings
Conclusions
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