Current Management of Craniopharyngiomas

Abstract

This paper reviews the current management of craniopharyngioma tumors with a focus on surgical treatment options. Advances in transnasal endoscopic skull base surgery and proton therapy have altered the management options available for this challenging condition. Craniopharyngiomas are benign suprasellar tumors that originate from Rathke’s pouch. These complex lesions may cause major neurologic, endocrine, and visual deficits. Treatment modalities include endoscopic transnasal versus open transcranial surgery to achieve gross total or subtotal resection. Various forms of radiation therapy are often integral to comprehensive management of craniopharyngiomas. This article reviews current treatment modalities and surgical risks, highlighting differences between endoscopic versus transcranial surgical approaches.