Abstract

Drug–drug interactions (DDIs) pose a major problem to patient safety. eHealth solutions have the potential to address this problem and generally improve medication management by providing digital services for health care professionals and patients. Clinical decision support systems (CDSS) to alert physicians or pharmacists about DDIs are common, and there is an extensive body of research about CDSS for professionals. Information about DDIs is commonly requested by patients, but little is known about providing similar support to patients. The aim of this scoping review was to explore and describe current knowledge about providing digital DDI services for patients. Using a broad search strategy and an established framework for scoping reviews, 19 papers were included. The results show that although some patients want to check for DDIs themselves, there are differences between patients, in terms of demands and ability. There are numerous DDI services available, but the existence of large variations regarding service quality implies potential safety issues. The review includes suggestions about design features but also indicates a substantial knowledge gap highlighting the need for further research about how to best design and provide digital DDI to patients without risking patient safety or having other unintended consequences.

Highlights

  • IntroductionPublisher’s Note: MDPI stays neutral with regard to jurisdictional claims in published maps and institutional affiliations

  • This paper contributes with an overview of current knowledge regarding development and provision of digital drug–drug interactions (DDI) services for patients

  • From the literature it is clear that at least some patients want to check for DDIs themselves, regarding both prescribed medications and self-medication

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Summary

Introduction

Publisher’s Note: MDPI stays neutral with regard to jurisdictional claims in published maps and institutional affiliations. Pharmaceutical treatment is an essential part of health care and enables the cure and prevention of many conditions. Drug-related problems (DRPs) are frequent and cause suffering for patients, and substantial costs for society [1,2,3,4,5]. DRPs are a common reason for hospital care and they can sometimes be fatal [1,4,5,6,7,8].

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