Abstract
Trypanosoma cruzi has existed in humans for >9000 years 1. Parasite, vector and human disease were described by Carlos Chagas in 1909 2. Vectorial and congenital transmissions account for ~70% and 26% of new infections, respectively. The clinical course of Chagas Disease (CD) is generally presented with acute parasitemic phase, clinically asymptomatic indeterminate phase, and chronic phase when patients develop cardiac, colon, or neurological disorders. Heart failure is recognized as the major cause of death in CD patients. The global productivity gain by treating acute or chronic CD and preventing heart failure and death is estimated to be $8 billion US dollars in 2021-2030 3. Thus, just the economic benefits make a strong case for new investments in controlling this disease.
Highlights
Trypanosoma cruzi has existed in humans for >9000 years 1
I propose that a standardized diagnostic algorithm as we proposed in Rios et al 9 should be adopted by all countries for identifying congenital infection and follow up and treat the infected infants
While heart is the primary target organ, megacolon and neurological disorders are noted in Chagas Disease (CD)
Summary
Trypanosoma cruzi has existed in humans for >9000 years 1. I believe increased diagnosis of infection in endemic rural areas and coordination and collaboration among various agencies within and between countries where shared experience can offer the accurate data on the rate of infection and Historial del artículo Recibido: 13 abr 2021 Aceptado: 16 abr 2021 Disponible en línea: 1 may 2021
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