Current data on the treatment of venous thromboembolic disease

Abstract

Venous thromboembolism disease is frequently seen in medical practice. Its morbidity, mortality and long-term sequels, as well as its haemorrhagic iatrogenic complications, represent a major problem of public health. For therapeutic management, we can usually use in medical practice non-fractionated heparin or low molecular weight heparin, sometimes substituted by antivitamin K therapy. Vena cava filter, surgical thrombectomy or thrombolytic therapy are rarely used. Elastic contention should by systematically prescribed. Therapeutic guidelines have been published on the recommendation furnished by randomised controlled trials. Low molecular weight heparin and early substitution by antivitamin K permitted an ambulatory treatment for deep vein thrombosis. The optimal duration of anticoagulant therapy is still controversial. Adequate biological survey causes decreasing incidence of haemorrhagic complications.