Abstract

The article presents a clinical case of a patient with antiphospholipid syndrome (APS), with a history of deep vein thrombosis and recurrent miscarriage. The methods of additional therapy for APS during pregnancy, which are used in cases of miscarriage refractory to the standard treatment, are described: administration of intravenous immunoglobulin, plasma exchange, glucocorticosteroids. The literature data on the use of additional APS therapy in pregnancy are given.

Highlights

  • ■ В статье приведен клинический случай пациентки с антифосфолипидным синдромом (АФС), имеющей в анамнезе тромбоз глубоких вен и привычное невынашивание

  • ■ The article presents a clinical case of a patient with antiphospholipid syndrome (APS), with a history of deep vein thrombosis and recurrent miscarriage

  • The methods of additional therapy for APS during pregnancy, which are used in cases of miscarriage refractory to the standard treatment, are described: administration of intravenous immunoglobulin, plasma exchange, glucocorticosteroids

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Summary

Клинические критерии

1. Cосудистые тромбозы: • один или несколько эпизодов подтвержденного артериального, венозного тромбоза или тромбоза мелких сосудов в любом органе или ткани, или 2. Патология беременности: • одна или более одной необъяснимой гибели морфологически нормального плода в 10 или более недель беременности с нормаль-

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