Abstract
Pneumonia of unknown cause detected in Wuhan; China was first reported to the WHO Country Office in China on December 31 2019. Later, the causative agent of which was identified to be Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). On March 11, 2020, the pandemic caused by the SARS-CoV-2 was termed as COVID-19 by the World Health Organization (WHO), with the disease touching practically every country in the world. The SARSCoV- 2 infection is, although characterized by flu-like symptoms, the fast progression is attributed to the acute respiratory distress syndrome (ARDS) [1] or myocarditis [2]. Many other manifestations of the disease have been described in different patient groups across different countries. As of June 18, 2020 the total infections globally stand at 8,242, 999 million people, with 445, 535 deaths, 4,530,266 recoveries. The take-home message is that despite the severity, there are more recoveries.
Highlights
Nitin Saksena*Epigenes Australia Pty Ltd, Australia *Corresponding author: Nitin Saksena, Epigenes Australia Pty Ltd., Melbourne, Australia
Pneumonia of unknown cause detected in Wuhan; China was first reported to the World Health Organization (WHO) Country Office in China on December 31 2019
A recent randomized, controlled, and an openlabel trial with 199 hospitalized adult patients in Wuhan/China with certain SARS-CoV-2 infection and pneumonia, the oral administration of twice-daily 400 mg lopinavir and 100 mg ritonavir for 14 days showed that the treatment with lopinavir/ritonavir combination was not associated with a reduction of viral RNA loads or duration of viral RNA detectability as opposed to 100 controls [28]
Summary
Epigenes Australia Pty Ltd, Australia *Corresponding author: Nitin Saksena, Epigenes Australia Pty Ltd., Melbourne, Australia. To Cite This Article: Nitin Saksena.Current and Future Challenges In Drug Therapeutics for Sars-Cov-2 Infection in Covid-19 Pandemic.
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