Abstract
Current advances in the function and biogenesis of peroxisomes and their roles in health and disease
Highlights
The 7th Open European Peroxisome Meeting (OEPM) was held on the 15th and 16th of October 2020 due to the Corona pandemic as ZOOM conference
This study provides new insights into peroxisome functions in cancer progression and offers the basis to study novel treatment strategies for kidney cancer
While peroxisomal import of several PTS1 proteins does not seem to be affected by phosphomimetic mutations at the Serine 232, the import efficiency of catalase with a non-canonical targeting signal sequence is suppressed in CHO cells, likewise counteracting against ROS species including H2O2 (Okumoto et al 2020)
Summary
The 7th Open European Peroxisome Meeting (OEPM) was held on the 15th and 16th of October 2020 due to the Corona pandemic as ZOOM conference. The results obtained using peroxisome-targeted fluorescent ATP indicator proteins and CRISPR generated cell models with selective deletion of single or several genes, suggested that ABCD (ATP-binding cassette subfamily D) transporters may function as ATP transporters.
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