Abstract
Curcumin is a pivotal spice and ayurveda medication mostly used in India and other Asian countries. The curcumin is been part of people for centuries as a detoxificant, pain reliever, anti-inflammatory agent and it has also demonstrated to have anti-cancer properties. Fluoride is becoming an irreversible environmental pollutant causing various alignments in both humans and animals on chronic exposure. The ameliorative studies in developing rats were studied in presence of Curcumin against sodium fluoride induced oxidative stress. Curcumin (10mg/kg body wt) was orally administered to NaF (20 ppm fluoride) induced rats for 53 days. The behavioural study such as Rota rod was conducted at 21 st and 30 th day. The brains of 1, 7, 14, 21 and 30 th day old pups were collected and analysed to check the levels of oxidation markers such as SOD, catalase and LPO. The levels of SOD and Catalase increased and whereas LPO were decreased with treatment of Curcumin. The results suggest that the Curcumin ameliorated the NaF induced alterations and proved to an excellent protective agent.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
