Abstract
Background Because of its diverse range of use in several ethics of diagnosis and care of multiple diseases, nanotechnology has seen remarkable growth and has become a key component of medical sciences. In recent years, there has been rapid advancement in medicine and biomaterials. Nanomedicine aids in illness prevention, diagnosis, monitoring, and treatment. Aim The purpose of this work is to evaluate the antibacterial, anti-inflammatory, and cytotoxic capabilities of green produced silver nanoparticle with the addition of curcumin-assisted chitosan nanocomposite (SCCN) against wound pathogenic as reducing agents. Materials and Methods The plant extract of Pongamia pinnata, silver nanoparticles, and its based curcumin nanoformulations was studied in this study utilizing UV visible spectrophotometer, selected area electron diffraction (SAED), and TEM. Anti-inflammatory, antimicrobial, and cytotoxic tests were performed on silver nanoparticles with the addition of curcumin-assisted chitosan nanocomposite (SCCN). Furthermore, these produced nanocomposites were coated on clinical silk and tested for antibacterial activity. Results The produced silver nanoparticle with the addition of curcumin-assisted chitosan nanocomposite (SCCN) has significant antibacterial activities against Pseudomonas aeruginosa and staphylococcus aureus. They are as well as possess anti-inflammatory activity and furthermore prove to be biocompatible. Conclusion This advancement in the field of biomaterials, which means nanocomposite, not only helps to reduce the harmful effects of pathogenic organisms while representing an environmentally benign material but it also shows to be a material with zero danger to humans and the environment.
Highlights
Nanotechnology has grown tremendously in the last decade, becoming an essential component of medical sciences as a result of its broad variety of applications in many concepts of illness investigation and therapy [1]
UV-Vis spectroscopy was used to examine the creation of silver nanoparticles with the addition of curcuminassisted chitosan nanocomposite (SCCN)
It is found that silver nanoparticles with the addition of curcumin-assisted chitosan nanocomposite (SCCN) have a significant function and strong antibacterial, anti-inflammatory, and cytotoxicity actions, inhibiting bacterial growth at low drug concentrations
Summary
Nanotechnology has grown tremendously in the last decade, becoming an essential component of medical sciences as a result of its broad variety of applications in many concepts of illness investigation and therapy [1]. Aim. The purpose of this work is to evaluate the antibacterial, anti-inflammatory, and cytotoxic capabilities of green produced silver nanoparticle with the addition of curcumin-assisted chitosan nanocomposite (SCCN) against wound pathogenic as reducing agents. Anti-inflammatory, antimicrobial, and cytotoxic tests were performed on silver nanoparticles with the addition of curcumin-assisted chitosan nanocomposite (SCCN) These produced nanocomposites were coated on clinical silk and tested for antibacterial activity. The produced silver nanoparticle with the addition of curcumin-assisted chitosan nanocomposite (SCCN) has significant antibacterial activities against Pseudomonas aeruginosa and staphylococcus aureus. They are as well as possess antiinflammatory activity and prove to be biocompatible. This advancement in the field of biomaterials, which means nanocomposite, helps to reduce the harmful effects of pathogenic organisms while representing an environmentally benign material but it shows to be a material with zero danger to humans and the environment
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
