Curative observation of preoperative superselective embolization of large-hypervascular meningioma

Abstract

Objective To evaluate of preoperative embolization with Glubran 2 glue before surgical resection of large-hypervascular meningiomas (LHMs). Methods Sixteen patients, admitted to our hospital from January 2008 to April 2014, were selected in our study; 12 of them were performed preoperative DSA and embolization with Glubran 2 glue (embolization group) and 4 of them did not accept embolization (non-embolization group); retrospective analysis of the clinical data and treatment efficacy of the two groups was performed. Results DSA showed that the blood fed to tumors were completely blocked (100%) in 4 patients, and great partly (90%) in 3 and partly (75%) in 5 patients of the embolization group. Postoperative complications were not noted in the patients of embolization group. As compared with those in the non-embolization group, the total tumor removal rate (100% vs. 75%) was significantly higher in the embolization group, and the intra-operative bleeding was obviously reduced, and the operation time was greatly shortened in the embolization group. Conclusion Preoperative transarteial embolization of meningiomas can reduce intra-operative bleeding, improve operation safety and total tumor resection. Key words: Preoperative Embolization; Large-hypervascular meningioma; Glubran 2 glue