Curative effect analysis on long-term intervention of liver hemangioma with different types of blood supply

Abstract

Objective: To compare the interventional curative effect of liver hemangioma patients with different types of blood supply treated by transcatheter arterial embolization (TAE) and portal vein interventional therapy. Methods: From January 2008 to December 2013, 324 patients definitely diagnosed as liver hemangioma were retrospectively analyzed. The patients were classified by blood supply as follows: hypervascular (128 cases) , moderate (104 cases) , hypovascular (90 cases) and portal vein type (2 cases) . The first three groups were treated by TAE with the injection of pingyangmycin-lipiodol emulsion and gelatin sponge, while the patients in last group were treated by portal vein embolization. The drug dosage of different types of hemangioma during operation, change of tumor size and curative effect after different follow-up periods were comparatively analyzed. Results: The two portal vein cases were not involved in the statistical analysis. The dose of pingyangmycin-lipiodol emulsion was the highest in hypervascular type and moderate type was the following and the least was in hypovascular type. In the follow-up of 3 to 6 months, the changes in tumor size of each group were compared with one another. The reduction of tumor size was the most in hypervascular type, moderate type was following and the least is in hypovascular type. The tumor reduction of hypervascular type had no difference with that of the moderate type in the follow-ups of 6 to 12 months, 1 to 2 years and 2 to 3 years. However, the hypovascular type, with the least tumor reduction, had obvious difference from the first two groups in all follow-ups. The effective rates of hyper-and moderate blood supply types were up to 100% and were higher than those of hypovascular group 2 or 3 years after the treatment, with significant difference. Conclusions: The curative effect of TAE for treatment of liver hemangioma has a obvious relationship with blood supply type that the hypervascular and moderate types were better than hypovascular type. Key words: Liver hemangioma; Interventional treatment; Embolization; Blood supply type