Abstract
Due to recent advancements in the production of experimental proteomic data, the Saccharomyces genome database (SGD; www.yeastgenome.org) has been expanding our protein curation activities to make new data types available to our users. Because of broad interest in post-translational modifications (PTM) and their importance to protein function and regulation, we have recently started incorporating expertly curated PTM information on individual protein pages. Here we also present the inclusion of new abundance and protein half-life data obtained from high-throughput proteome studies. These new data types have been included with the aim to facilitate cellular biology research. Database URL: www.yeastgenome.org
Highlights
The Saccharomyces genome database (SGD; www.yeastge nome.org) is the premier community resource for curated data about the model organism Saccharomyces cerevisiae [1]
As part of the SGD project we curate experimental protein results, with basic information summarized on the Locus Summary pages, and more detailed information presented on individual protein pages [2]
The protein information housed at SGD can be used to direct experimental research aimed at elucidating protein function and biological role in the context of the cell
Summary
The Saccharomyces genome database (SGD; www.yeastge nome.org) is the premier community resource for curated data about the model organism Saccharomyces cerevisiae [1]. The protein information housed at SGD can be used to direct experimental research aimed at elucidating protein function and biological role in the context of the cell. Protein pages contain a descriptive overview of the protein in question (Figure 1), experimental data such as protein abundance and protein half-life, structural domain information, primary amino acid sequence from a variety of strains with overlaid experimental post-translational modification (PTM) data, physico-chemical properties derived from the protein sequence, a list of external identifiers and links to other resources that may be useful to researchers (Table 1).
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