Abstract
1. The curariform activity of a new series of bis-quaternary ammonium compounds is reported. 2. Moderate increase of activity is obtained by shortening the distance between nitrogen atoms from approximately 15 Å to 9 Å. 3. Replacement of N-ethyl groups with N-methyl in the 6-carbon chain analog decreases both the activity and the subcutaneous absorption in mice, but has no effect on the activity as measured in dogs and rabbits.
Full Text 
Sign-in/Register to access full text options
Sign-in/Register to access full text options 
Paper version not known
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
