Abstract
Purpose: Over one million individuals live with a lower limb amputation (LLA) in the United States, with 80% of those amputations caused by non-traumatic etiologies including vascular complications from severe diabetes mellitus (DM). Individuals with DM and unilateral LLA (DM+LLA) and individuals with DM who have not undergone LLA (DM group) demonstrate alterations in gait biomechanics compared to healthy individuals (healthy group). This indicates gait alterations in individuals with DM+LLA may be influenced not only by prosthesis use but also by mobility limitations present with severe DM.
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