Abstract

Since ancient times, herbs and spices have enjoyed rich tradition for their flavor enhancement characteristics and for their medicinal properties. Ayurveda prescribes more than 700 plant based medicines that contain spices and food additives to encourage good health. Diet is an important factor in prevention of diseases. Besides flavor and taste to cuisines, they also improve immune system. Taking this into consideration, the present study was planned to evaluate the antigenotoxic potential of methanolic extract of Cuminum cyminum (MCC extract) and Coriandrum sativum (MCS extract) against the mutagenicity of chromium trioxide (CrO3) using Allium cepa root chromosomal aberration assay. MCC and MCS extracts inhibited the chromosomal aberrations (both physiological and clastogenic) induced by CrO3 (8 ppm).

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