Abstract

FITC-labelled monoclonal antibody typing reagents for herpes simplex virus (HSV) (PathoDx, Diagnostic Products Corp., Los Angeles, California) were compared to another commercially available FITC-labelled monoclonal antibody typing reagent for culture confirmation and typing of HSV isolates from clinical specimens. A total of 344 clinical specimens were evaluated for culture confirmation and typing by the two systems. There were 296 HSV-positive cultures identified by cytopathic effect (CPE). The PathoDx typing reagents identified 143 isolates as HSV-1, and 151 isolates as HSV-2, with two isolates staining with both the type 1 and type 2 reagent. The PathoDx typing reagents had a 100% concordance with the other set of typing reagents.

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