Abstract
BLACKHEAD (entero-hepatitis), a widespread and generally fatal disease of turkeys, was attributed to a protozoon, Amaeba meleagridis, by Theobald Smith1. Later, Tyzzer confirmed its presence in caecal lesions and renamed it Histomonas (gen. nov.) meleagridis Smith2. Although there is no difficulty in infecting young chickens experimentally with H. meleagridis (Tyzzer3) the disease produced is not severe, and the chickens soon recover clinically, though they may remain carriers, passing Protozoa in their faeces, for long periods. Theobald Smith4 saw Amaeba (= Histomonas) meleagridis in liver sections from diseased fowls, and Tyzzer5 found similar lesions in a two-year-old hen. Although Drbohlav6 and afterwards Tyzzer7 cultivated Histomonas meleagridis from the caecal discharges of experimentally infected chickens, all attempts to cultivate the parasite from diseased tissues from either turkeys or chickens failed (Tyzzer7).
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