Abstract

Regenerative therapy is a cutting-edge therapeutic strategy used in periodontics with the goal of restoring the health and functionality of the tissues that support teeth, including the periodontal ligament, bone and gums. These supporting tissues can be destroyed by periodontal disorders, including gingivitis and periodontitis, which may result in tooth loss. Regenerative therapy encourages the regeneration of missing or damaged tissues in an effort to undo or heal this damage. Biological solutions to biological problems are emerging as a new paradigm in dentistry and medicine. Scientific discoveries in cellular, developmental and molecular biology have truly revolutionized our collective understanding of biological processes, human genetic variations, the continuity of evolution and the etiology and pathogenesis of thousands of human diseases and disorders. There have been a number of encouraging developments in periodontics and regenerative therapy. Guided Tissue Regeneration (GTR), osseous grafting and newer techniques like Platelet-Rich Plasma (PRP) and Platelet-Rich Fibrin (PRF), stem cell therapy, growth factors and biomaterial, gene therapy, 3D-printing and tissue engineering, anti-inflammatory drugs, microbiome-based therapy and minimally invasive methods have all advanced from these earlier approaches. The current improvements in regenerative therapy for periodontics that yield superior results are contextualized in this research.

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