Abstract
A novel method for achieving a copper(II)-catalyzed domino reaction for the construction of 2-aryl quinazolinones, without the addition of any ligand and additive, has been developed. The domino reaction achieved N-(alpha-substituted)benzylation, benzylic C-H amidation, and C-C (or C-H) bond cleavage. (C) 2014 Li-Xia Wang and Ya-Lin Tang. Published by Elsevier B.V. on behalf of Chinese Chemical Society and Institute of Materia Medica, Chinese Academy of Medical Sciences. All rights reserved.
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