Abstract
An efficient method for the synthesis of buta-1,3-diynes have been developed via copper(I) catalyzed homocoupling reaction of terminal acetylenes in presence of CuI and tetramethylethylenediamine (TMEDA) at 100 ºC for 3.0 h under solvent-free conditions. This efficient methodology allowed the homocoupling of five terminal alkynes in moderate to excellent yields.
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