CuI catalyzed-novel one-pot synthesis of aryl alkenyl thioethers through Ullmann-type coupling reactions using carbon disulfide as a sulfur surrogate in the presence of nitroalkanes and aryl iodides

Abstract

A mild, general and efficient copper-catalyzed system for C-S bond formation is developed. With CuI as catalyst and l-Proline as ligand, the S-arylation of nitroalkane-CS2 adducts with aryl iodides were performed under mild conditions to give the corresponding products in good to excellent yields.