Abstract
Cu(I)-catalyzed intramolecular annulation of o-ethynylquinoline-3-carbaldehydes leads to the synthesis of alkoxy/imidazole-substituted 1,3-dihydrofuro[3,4-b]quinolines via C-O and C-N bond formation. The scope of the reaction was further extended to o-ethynylquinoline-3-carbonitriles for the synthesis of alkoxy-substituted 3H-pyrrolo[3,4-b]quinolines using alcohols as nucleophiles. These reactions are regioselectively favoring the 5-exo-dig cyclizations in all the annulation processes.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
