CTSC-Net: an effectual CT slice classification network to categorize organ and non-organ slices from a 3-D CT image.

Abstract

Computed tomography (CT) is a non-invasive diagnostic imaging modality that reveals more insight into human organs than conventional X-rays. In general, the CT output is a 3-D image that is formed by combining multiple 2D images or slices together. It is essential to keep in mind that not all of the slices provide significant information to detect tumours. Usually, a 3-D CT image obtained from the CT scanners has a significant number of unwanted non-organ slices in it. Radiologists typically devote a significant amount of time to select the slices with organ from a 3-D CT image. The presence of a tumour is only evident in the organ slice; hence, radiologists must be cautious not to skip any organ slices. This work is evaluated on the LITS, 3DIRCADb and COVID-19 CT datasets. The three datasets collectively contain 22,435 organ slices and 53,661 non-organ slices, and there is a huge gap between the number of organ and non-organ slices. There is a need for the automatic elimination of non-organ slices in 3-D CT volumes to assist the physicians, and hence, this work focuses on the automatic recognition of organ slices from 3-D CT volumes. In this paper, a new deep model called the computed tomography slice classification network (CTSC-Net) is proposed for CT slice classification between organ and non-organ slices. The model is trained on 77,980 CT slices, validated on 9748 slices and tested on 12,571 slices. Nine CNN architectures with different layer settings are trained and tested to arrive at the final optimal model. The performance measures are computed in terms of true positive rate, true negative rate, sensitivity, specificity and accuracy. The 20-layer CTSC-Net achieves a validation accuracy of 95.04% and an overall testing accuracy of 99.96%. The proposed model is compared to eight different pre-trained CNN models, and the results of the proposed CTSC-Net surpassed all the comparable models. The activation feature maps of different layers of the CTSC-Net are visualized to verify the discriminative features learned by the network. Hence, the proposed CTSC-Net can be employed as a computer-aided diagnosis tool to help physicians discard unnecessary non-organ slices from the 3-D CT volume and to speed up the CT diagnosis process.