Abstract
s / Pancreatology 13 (2013) S1–S80 S21 were excluded. The median time interval between the onset of AP and admission was 24 (09:48) hours. According to KDIGO AKI criteria, patients were divided into four groups: without AKI (n1⁄480) 53%, 1st stage (n1⁄435) 23%, 2nd stage (n1⁄422) 14%, 3rd stage (n1⁄415) 10%. Results: Significant differences (p<0.05) in severity condition (APACHE II, Ranson, SOFA scores) were found among all groups except for data between groups with 2nd and 3rd stages (Table). The 60-day Kaplan-Meier survival plot (Figure) shows a diversion of the survival rates among the groups (p1⁄40.000). There was no significant difference between the groups without AKI and 1st stage (hospital mortality rates were 23% and 34% respectively, (p1⁄40.415)) compared to a large increase in mortality (early phase of disease) in groups with 2nd and 3rd stages (hospital mortality rates 64% and 60% respectively, (p1⁄40.727)). Conclusions: The development of AKI (47% of the ICU patients with AP) is associated with worse clinical outcome. Timely recognition of severe disease and applying appropriate therapy (1st stage of AKI and earlier) are extremely important in management of patients with OF.
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