Abstract

This chapter, found in the chest pain section of the book, provides a succinct synopsis of a key study comparing the use of computed tomography angiography (CTA) and ventilation-perfusion (V-Q) scans for ruling out pulmonary embolism. This summary outlines the study methodology and design, major results, limitations and criticisms, related studies and additional information, and clinical implications. The researchers report that a strategy to rule out pulmonary embolism and anticoagulation therapy using the methods in the study resulted in low, similar rates of venous thromboembolic events at 3 months follow-up; however, more patients were diagnosed with pulmonary embolism in the CTA arm of the study. In addition to outlining the most salient features of the study, a clinical vignette and imaging example are included in order to provide relevant clinical context.

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