CT and MR Findings of Intracranial Ganglioglioma

Abstract

Purpose : The purpose of this study was to evaluate clinical, CT and MRI findings of intracranialganglioglioma. Materials and Methods : All patient were between 9 and 30 years old , and were men. Four patientswith pathologically proved gangliogliomas were included in this study. CT and MR images were assessedretrospectively for location, type, density, signal intensity and contrast enhancement pattern of tumors. Results: All patients suffered from epileptic seizure of long history. The tumors were located in temporal lobe(3 cases)and frontal lobe(1 case). The type of tumor were solid (2 cases) and cystic(2cases). On the CT scan, the cysticlesions were hypodense and the solid lesions were isodense to normal brain parenchyme. Calcification within lesionwas noted in 3 cases. On the MR imaging, cystic lesions reveal high signal intensity on T2-weighted image(T2WI)and low signal intensity on T1-weighted image(T1WI). One of the solid lesion showed iso-signal intensity on T1WIand high signal intensity on T2WI. Another revealed high signal intensity on both T1WI and T2WI. The signalintensity of the calcifications(3case) was variable. Two cases showed signal void, one case revealed high signalintesnity on T1WI and low signal intensity on T2WI. In three patients, the lesions enhanced after intravenousadministration of Gd-DTPA. Conclusion : Ganglioglioma should be considered in the differential diagnosis when thechildren or young male with epilepy have a cystic mass with calcification or ill- defined solid mass , especiallyin temporal lobe on CT or MRI.