Abstract
(1) Background: Computer tomography (CT) scanning is currently the standard method for staging of colon cancer; however, the CT based preoperative local staging is far from optimal. The purpose of this study was to investigate the sensitivity and specificity of magnetic resonance imaging (MRI) compared to CT in the T- and N-staging of colon cancer. (2) Methods: Patients underwent a standard contrast-enhanced CT examination. For the abdominal MRI scan, a 3 Tesla unit was used, including diffusion weighted imaging (DWI). Experienced radiologists reported the CT and MRI scans blinded to each other and the endpoint of the pathological report. (3) Results: From 2018 to 2021, 134 patients received CT and MRI scans. CT identified 118 of the 134 tumors, whereas MRI identified all tumors. For discriminating between stage T3ab and T3cd, the sensitivity of CT was 51.1% and of MRI 80.0% (p = 0.02). CT and MRI showed a sensitivity of 21.4% and 46.4% in detecting pT4 tumors and a specificity of 79.0% and 85.0%, respectively. (4) Conclusion: Compared to CT, the sensitivity of MRI was statistically significantly higher in staging advanced T3cd and T4 tumors. MRI has the potential to be used in the treatment planning of colon cancer.
Highlights
Neoadjuvant chemotherapy holds the potential to improve the outcome of advanced colon cancer with effective control and reduction of tumor size [5,6,7]
The main purpose of the study was to investigate the applicability of 3 Tesla magnetic resonance imaging (MRI) in colon cancer by assessing the sensitivity and specificity, to clarify whether it is superior to Computer tomography (CT) scanning for the T, N-staging
We found the ability of CT and MRI to diagnose bowel wall penetration to be almost identical
Summary
Publisher’s Note: MDPI stays neutral with regard to jurisdictional claims in published maps and institutional affiliations. Colon cancer is among the most prevalent cancers [1]. Surgery was the only treatment; around half of the patients recurred with incurable disease. A moderate improvement in survival can be achieved for some patients with stage II and III colon cancer [2]. Neoadjuvant treatment has been shown to be effective [3,4]. Neoadjuvant chemotherapy holds the potential to improve the outcome of advanced colon cancer with effective control and reduction of tumor size [5,6,7]
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