Abstract
The sensitivity, specificity and predictive value of a Lyme CSF-PCR assay were evaluated in children from a Lyme-endemic region admitted to the Alfred I duPont Hospital for Children, Wilmington, DE, for suspected Lyme meningitis.
Highlights
The relation between cerebral blood flow and the clinical severity of symptoms in 45 autistic children, mean age 7.9 years, was determined at centres in Paris, France
The sensitivity, specificity and predictive value of a Lyme CSF-PCR assay were evaluated in children from a Lyme-endemic region admitted to the Alfred I duPont Hospital for Children, Wilmington, DE, for suspected Lyme meningitis
Lyme CSF-PCR was positive in 1 patient (5%) with Lyme meningitis and in 1 (1%) classified as aseptic meningitis
Summary
The relation between cerebral blood flow (rCBF) and the clinical severity of symptoms in 45 autistic children, mean age 7.9 years, was determined at centres in Paris, France. The sensitivity, specificity and predictive value of a Lyme CSF-PCR assay were evaluated in children from a Lyme-endemic region admitted to the Alfred I duPont Hospital for Children, Wilmington, DE, for suspected Lyme meningitis. Twenty met CDC criteria for Lyme meningitis, and 88 were diagnosed with aseptic meningitis, based on negative Lyme serology and absence of erythema migrans.
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