Abstract
Cerebrospinal (CSF) culture results were compared with results of blood cultures and CSF parameters (WBC, glucose, and protein) in 9111 neonates with culture-proven meningitis and a first lumbar puncture at >34 weeks’ gestational age from 150 NICU’s managed by the Pediatrix Medical Group.
Highlights
Cerebrospinal (CSF) culture results were compared with results of blood cultures and CSF parameters (WBC, glucose, and protein) in 9111 neonates with culture-proven meningitis and a first lumbar puncture at >34 weeks' gestational age from 150 NICU's managed by the Pediatrix Medical Group
A suspected diagnosis of neonatal meningitis should not be dismissed by a negative blood culture or normal CSF cells, glucose or protein
s chorea (SC) patients were female in 71%, the mean age at presentation was 9.8 years, chorea was unilateral in 30%, and 30% had a family history of acute rheumatic fever (ARF)
Summary
In the majority of young children with acute encephalopathy in this study, the earliest laboratory sign of CNS involvement was an abnormal CSF:serum albumin ratio and disruption of the blood-CSF barrier. The CSF:serum albumin ratio found abnormal in encephalopathy may prove helpful in the diagnosis and distinction from prolonged, focal or multiple FS. CSF CULTURES AND BACTEREMIA IN NEONATAL MENINGITIS
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