Crystal structure of methyl 3-amino-2,3-dideoxy-β- d- arabino-hexopyranoside. Stabilization of the crystal lattice by a double network of N–H⋯O, O–H⋯N and O–H⋯O interactions

Abstract

The structure, conformation and configuration of methyl 3-amino-2,3-dideoxy-β- d- arabino-hexopyranoside were investigated by 1H NMR, 13C NMR and IR spectroscopy, as well as by optical rotation. The crystal structure was confirmed by single-crystal X-ray crystallographic analysis at 293 K and R = 0.0434 based on 910 independent reflections. The crystal belongs to the monoclinic system, space group of P2 1 with cell dimensions a = 6.050(1) Å, b = 7.284(1) Å, c = 10.289(2) Å, β = 104.69(3)°, D c = 1.341 Mg cm −3 and V = 438.9(1) Å 3 for Z = 2. Furthermore, the molecule has a typical 4 C 1 chair conformation. Hydrogen bonds between sugar molecules are responsible for stabilizing the crystal lattice.