Abstract
The Structural and Genomics Informa-tion Laboratory is involved in a Structural and FunctionalGenomics program (BIGS; http://www.igs.cnrs-mrs.fr/str_gen/) aiming at the discovery of new antibacterialtargets among proteins that are ubiquitous in bacterialpathogens, exhibiting good sequence conservation, butwhose precise biochemical or cellular functions remainunknown.Comprehensivebioinformaticsandcomparativegenomics analyses were performed according to thesecriteria, resulting in the selection of 110
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