Abstract
The title compound, C17H18N2O2S2, synthesized via a condensation reaction between S-benzyl di-thio-carbazate and 3,4-di-meth-oxy-benzaldehyde, crystallized with two independent mol-ecules (A and B) in the asymmetric unit. Both mol-ecules have an L-shape but differ in the orientation of the benzyl ring with respect to the 3,4-di-meth-oxy-benzyl-idine ring, this dihedral angle is 65.59 (8)° in mol-ecule A and 73.10 (8)° in mol-ecule B. In the crystal, the A and B mol-ecules are linked via pairs of N-H⋯S hydrogen bonds, forming dimers with an R 2 (2)(8) ring motif. The dimers are linked via pairs of C-H⋯O hydrogen bonds, giving inversion dimers of dimers. These units are linked by C-H⋯π inter-actions, forming ribbons propagating in the [100] direction.
Highlights
The title compound, C17H18N2O2S2, synthesized via a condensation reaction between S-benzyl dithiocarbazate and 3,4-dimethoxybenzaldehyde, crystallized with two independent molecules (A and B) in the asymmetric unit
The dimers are linked via pairs of C—H O hydrogen bonds, giving inversion dimers of dimers
Schiff bases have been proven to possess a variety of biological activities, and this has led to extensive studies on this group of compounds with particular emphasis on those derived from dithiocarbazates
Summary
Schiff bases have been proven to possess a variety of biological activities, and this has led to extensive studies on this group of compounds with particular emphasis on those derived from dithiocarbazates. Dithiocarbazate-derived Schiff bases have generally been found to exhibit interesting cytotoxic and antimicrobial activities. One of the most investigated dithiocarbazates has been S-benzyldithiocarbazate (SBDTC). Whose derivatives have shown promising biological activities (Break et al, 2013). As part of our research which is aimed at developing anticancer and antimicrobial drugs, we have synthesized a novel Schiff base via the condensation reaction of SBDTC and 3,4-dimethoxybenzaldehyde. We report on the synthesis and crystal structure of the title compound
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: Acta Crystallographica Section E Crystallographic Communications
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
