Abstract
The crystal structure of an epalrestat methanol solvate (C15H13NO3S2·CH3OH) was determined by X-ray crystallography. The compound crystallized in a monoclinic system and was characterized as follows: P2/c, a = 14.1757(3)Å, b = 8.2338(2)Å, c = 28.6476(6)Å, β = 102.0075(7)°, Z = 8, V = 3270.6(1)Å3. The epalrestat molecules formed hydrogen bonds with methanol solvent molecules between the carboxyl group of one epalrestat, the hydroxyl group of the methanol, and the carbonyl group of the rhodanine ring in another epalrestat.
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