Abstract
9-Amino-acridinium chloride N,N-di-methyl-formamide monosolvate, C13H11N2 +Cl-·C3H7NO, crystallizes in the monoclinic space group P21/c. The salt was crystallized from N,N-di-methyl-formamide. The asymmetric unit consists of two C13H11N2 +Cl- formula units. The 9-amino-acridinium (9-AA) mol-ecules are protonated with the proton on the N atom of the central ring. This N atom is connected to an N,N-di-methyl-formamide mol-ecule by a hydrogen bond. The H atoms of the amino groups create short contacts with two chloride ions. The 9-AA cations in adjacent layers are oriented in an anti-parallel manner. The mol-ecules are linked via a network of multidirectional π-π inter-actions between the 9-AA rings, and the whole lattice is additionally stabilized by electrostatic inter-actions between ions.
Highlights
Chemical contextAminoacridine (AA) derivatives exhibit antibacterial (Ciric et al, 2011), anticancer (Hassan et al, 2011), antiviral (Kaur & Singh, 2011) and antiprion effects (Villa et al, 2011), as well as other therapeutic properties (Muregi & Ishih, 2010)
9-Aminoacridinium chloride N,N-dimethylformamide monosolvate, C13H11N2+ClÀÁC3H7NO, crystallizes in the monoclinic space group P21/c
The 9-aminoacridinium (9-AA) molecules are protonated with the proton on the N atom of the central ring
Summary
Aminoacridine (AA) derivatives exhibit antibacterial (Ciric et al, 2011), anticancer (Hassan et al, 2011), antiviral (Kaur & Singh, 2011) and antiprion effects (Villa et al, 2011), as well as other therapeutic properties (Muregi & Ishih, 2010). The synthesis of these compounds and analysis of their interactions is very useful in view of their importance in a wide range of different biological systems (Coupar et al, 1997). This publication reports the crystal structure of 9-aminoacridinium chloride N,N-dimethylformamide solvate (1:1)
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