Abstract
The title compound, C12H9N3O, is an intermediate in the synthesis of the muscarinic M2 receptor antagonist AFDX-384. The seven-membered ring adopts a boat conformation and the dihedral angle between the planes of the aromatic rings is 41.51 (9)°. In the crystal, molecules are linked into [001] chains of alternating inversion dimers formed by pairs of N—H⋯O hydrogen bonds and pairs of N—H⋯N hydrogen bonds. In both cases, R 2 2(8) loops are generated.
Highlights
The title compound, C12H9N3O, is an intermediate in the synthesis of the muscarinic M2 receptor antagonist AFDX384
Molecules are linked into [001] chains of alternating inversion dimers formed by pairs of N—HÁ Á ÁO hydrogen bonds and pairs of N—HÁ Á ÁN hydrogen bonds
We appreciate the financial support provided to NMR by the Deutscher Akademischer Austauschdienst (DAAD)
Summary
The title compound, C12H9N3O, is an intermediate in the synthesis of the muscarinic M2 receptor antagonist AFDX384. = 0.10 mmÀ1 T = 100 K 0.35 Â 0.26 Â 0.06 mm ISSN 2056-9890 Absorption correction: multi-scan (SADABS; Bruker, 2013) Tmin = 0.898, Tmax = 0.959
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