Abstract
In the title compound, C14H18N2O2S, the piperidine ring has a chair conformation. Its mean plane is twisted with respect to the 4-meth-oxy-benzoyl ring, with a dihedral angle of 63.0 (3)°. The central N-C(=S)-N(H)-C(=O) bridge is twisted with an N-C-N-C torsion angle of 74.8 (6)°. In the crystal, mol-ecules are linked by N-H⋯O and C-H⋯O hydrogen bonds, forming chains along the c-axis direction. Adjacent chains are linked by C-H⋯π inter-actions, forming layers parallel to the ac plane. The layers are linked by offset π-π inter-actions [inter-centroid distance = 3.927 (3) Å], forming a supra-molecular three-dimensional structure.
Highlights
In the title compound, C14H18N2O2S, the piperidine ring has a chair conformation
Its mean plane is twisted with respect to the 4-methoxybenzoyl ring, with a dihedral angle of 63.0 (3)
Bivalent and trivalent metal ions prefer to coordinate via the S and O atoms from the thiono and carbonyl units, respectively, but monovalent metal ions tend to coordinate via the S atom
Summary
Benzoylthiourea compounds exhibit anti-inflammatory (Brachmachari & Das, 2012), anti-cancer, anti-diabetic and anti-virus activity (Kovačková et al, 2011), and have applications as ionic sensors (Suhud et al 2015b) and pharmaceutical drugs (Watson et al, 2000). Benzoylthiourea molecules containing thioamide (NH—C S) and carbonyl (C O). Bivalent and trivalent metal ions prefer to coordinate via the S and O atoms from the thiono and carbonyl units, respectively, but monovalent metal ions tend to coordinate via the S atom. We report on the crystal structure of 4-methoxy-N(piperidine-1-carbonothioyl)benzamide (MPiCB) and its chemical structural data in comparison with the previously reported compound 4-methoxy-N-[(pyrrolidin-1-yl)carbonothioyl]benzamide (MPCB; Suhud et al, 2015a,b). A view of the molecular structure of the title compound (MPiCB), with the atom labelling.
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: Acta crystallographica. Section E, Crystallographic communications
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
