Abstract
Source of material: The title compound was prepared, according to ref. 1, from 3,7-bicyclo[3.3.1]nonanedione by the addition of phenylethinyllithium (tetrahydrofuran solutions, 195 К 278 К, 2h). Flash chromatography on silica gel with petroleum ether/ethyl acetate ( 1:1 ) of the crude product followed by recrystallization from the same solvent yielded colorless crystals, mp 420 К 421 К, in 79% yield. The title compound is an example for the 2-oxadamantan-l-ols that always arise by the addition of nucleophiles at 3,7-bicyclo[3.3.I]nonanedione. Rapid formation of the cyclic hemiacetal from the exo adduct of one nucleophile precludes addition of the second one (see ref. 2).
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More From: Zeitschrift für Kristallographie - New Crystal Structures
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