Crystal Structure of 2,5-Dibenzoyl-4-iodoaniline

Abstract

2,5-Dibenzoyl-1,4-diaminobenzene (1.0 g, 3.21 mmol) dissolved in ether (10 mL) was added to boron trifluoride etherate (1.6 mL, 12.85 mmol), followed by the addition of isoamyl nitrite (1.52 mL, 11.24 mmol). After the precipitate was isolated, it was added to a solution of sodium iodide (0.52 g, 3.53 mmol) and iodide (0.07 g, 0.32 mmol) in acetonitrile (20 mL). After 60 min, the mixture was poured into sodium thiosulfate aquation, extracted with dichloroethane, and dried over anhydrous magnesium sulfate. Finally, column chromatography (1:8, ethyl acetate/petroleum ether) gave the title compound (0.9 g, 66% yield). Its single crystal suitable for X-ray structural analysis was obtained by slowly evaporating from ethanol at room temperature for 10 days.A colorless crystal having dimensions of 0.10 ¥ 0.10 ¥ 0.05 mm