Crystal structure of 1-[2,4-bis(4-methoxy-phenyl)-3-azabicyclo[3.3.1]nonan-3-yl]ethanone.

V Shreevidhyaa Suressh,S Ponnuswamy,S Sathya,G Usha,A Akila

doi:10.1107/s1600536814022545

V Shreevidhyaa Suressh, S Ponnuswamy + Show 3 more

Open Access

https://doi.org/10.1107/s1600536814022545

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Abstract

In the title compound, C24H29NO3, the azabicycle contains two six-membered rings, viz. a cyclohexane ring and a piperidine ring. The first adopts a chair conformation and the second a half-chair conformation. The dihedral angle between their mean planes is 86.21 (13)°, indicating that they are almost perpendicular to one another. The dihedral angle between the planes of the 4-methoxyphenyl rings is 17.51 (13)°, and they make dihedral angles of 81.9 (3) and 81.3 (3)° with the ethan-1-one group. In the crystal, molecules are linked by C—H⋯π interactions forming chains along [10-1].

Highlights

In the title compound, C24H29NO3, the azabicycle contains two six-membered rings, viz. a cyclohexane ring and a piperidine ring
Molecules are linked by C—H
Azabicyclononanes are present in many alkaloids and they have immense biological activities (Jeyaraman & Avila, 1981; Hardick et al, 1996; Barker et al, 2005)

Summary

Introduction

C24H29NO3, the azabicycle contains two six-membered rings, viz. a cyclohexane ring and a piperidine ring. H-atom parameters constrained max = 0.36 e Å3 For the biological activity of piperidine derivatives, see: Barker et al (2005); Hardick et al (1996); Jeyaraman & Avila For the crystal structures of similar compounds, see: Parthiban et al (2008); Parthiban, Ramkumar et al (2009, 2010).

Results

Conclusion