Abstract
The tetra-hydro-pyridine ring of the quinoline system in the title compound, C14H13ClN2O2S, adopts a half-chair conformation with the bond-angle sum at the N atom being 350.0°. The dihedral angle between the least-squares planes of the two aromatic rings is 50.13 (11)°. In the crystal, inversion dimers linked by pairs of C-H⋯O hydrogen bonds generate R 2 (2)(10) loops. Additional inter-molecular C-H⋯O hydrogen bonds generate C(7) chains along [100].
Highlights
The tetrahydropyridine ring of the quinoline system in the title compound, C14H13ClN2O2S, adopts a half-chair conformation with the bond-angle sum at the N atom being 350.0
Inversion dimers linked by pairs of C—H O hydrogen bonds generate R22(10) loops
1,2,3,4-Tetrahydroquinoline derivatives play a vital role in developing pharmacological agents and they have been considered as potential drugs
Summary
Supporting information: this article has supporting information at journals.iucr.org/e. 1,2,3,4-Tetrahydroquinoline derivatives play a vital role in developing pharmacological agents and they have been considered as potential drugs 1990; Omura & Nakagawa, 1981) and antagonists for N-methyl-d-aspartate (NMDA) receptors at the glycine recognition site (Cai et al, 1996). We have synthesized a series of 1,2,3,4-tetrahydroquinoline derivatives and a few molecules exhibit pharmacological activity (unpublished results). In a continuation of our work on the derivatives of 1,2,3,4-tetrahydroquinolines (Jeyaseelan et al, 2014, 2015a,b), we report the synthesis and crystal structure of 1-[(6-chloropyridin-3yl)sulfonyl]-1,2,3,4-tetrahydroquinoline, (I)
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