Crystal structure and nuclease activity of mono(1,10-phenanthroline) copper complex

Abstract

The hydroxo-bridged dinuclear copper (II)/phen complex [Cu 2(phen) 2(OH) 2(H 2O) 2][Cu 2(phen) 2(OH) 2Cl 2]Cl 2.6H 2O (phen=1,10-phenanthroline) has been prepared and characterized by single crystal X-ray diffraction. The coordinated area of the complex shows two distorted [CuN 2O 2O w] and [CuN 2O 2Cl] square-pyramidal and one strictly planar configuration CuO 2Cu involving two O atoms of hydroxo-bridged, Cu 2+ cations, N atoms of two phen ligands and disorder solvate water and chlorine anions. In the presence of H 2O 2, the complex of mono(1,10-phenanthroline)copper exhibits higher activity as a nuclease than bis(1,10-phenanthroline)copper.