Abstract

An ingenious technique allows the monitoring of brain-wide patterns of neuronal activity in a vertebrate at the cellular level, while the animal interacts with a virtual environment. See Article p.471 Improvements in technology have allowed neuroscientists to dissect the relationship between behaviour and activity in specific neural circuits. However, in a model system such as the zebrafish, it is potentially possible to track neural activity in circuits on a much broader scale. Using a virtual-reality-based imaging system, Florian Engert and colleagues track the dynamics of adaptive locomotion at single-neuron resolution in navigating fish to derive candidates for functional elements that drive motor learning.

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