Abstract
The X-ray crystal structures of 4,4′-dihydroxybenzophenone-2,4-dinitrophenylhydrazone (I) and 2,2′-dihydroxybenzophenone-2,4-dinitrophenylhydrazone (II) have been determined in order to study the structural characteristics of these molecules that may contribute to their antiestrogenic and cytotoxic properties. These structures have been compared to other hydrazone derivatives as well as tamoxifen, an antiestrogen drug presently used clinically for the treatment of breast cancer.
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