Abstract
In September of 1986, on a swine breeding farm in Saga Prefacture, three-33-day-old, weanling piglets were stricken with diarrhea. As a result, two piglets died and one was in a moribund state immediately after the onset of diarrhea.Histological examination confirmed numerous round protozoa in the epithelial cells lining the crypts of the cecum and the colon of the dead and moribund piglets. The protozoa were 1.5 to 5μm in diameter and were PAS positive. Electron microscopic examination revealed the protozoa in various stages of the development and the disappearance of microvilli at the affected colon. Characteristic findings observed in the present cases corresponded to those previously reported on Cryptosporidiosis.Due to the findings of catarrhal enteritis in the non-infected small intestine, marked demyelination of the central nervous system of the moribund piglets and OPG obtained in the other healthy piglets of the same litter, some factor other than cryptosporidiosis also be involved.
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