Abstract
Aim: The present study was taken up to establish the effect of niacinamide on phenoloxidase lead melanogenesis and to prove the reliability of C. neoformans based screening methodology.
 Methods: The organism was grown in the Minimal media in presence and absence of L- DOPA and Niacinamide and checked for its pigment producing ability at different time intervals.
 Results: Niacinamide did not affect the pigmentation in Cryptococcus neoformans in the absence or presence of L-Dopa.
 Conclusion: Cryptococcus neoformans as a biological tool for studying the mechanism of action of various melanin promoters/ inhibitors. The present study highlights the importance and usefulness of Cryptococcus neoformans based screening invention as it is cost effective rapid and ‘living cell model’.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
