Abstract

Primary intestinal lymphangiectasia (Waldmann's disease) is a rare exudative enteropathy without precisely assessed infectious risk. We report the case of a 49-year-old male patient with meningitis and cerebral vasculitis due to Cryptococcus neoformans complicating Waldmann's disease diagnosed 12years ago. The treatment combined liposomal amphotericin B, 3mg/kg daily plus flucytosine 25mg/kg/6h, both intravenously during 15days, then fluconazole 800mg daily during 8weeks, and finally 200mg daily indefinitely. Dexamethasone 0.4mg/kg daily during the first week was gradually decreased over 2months. The outcome was good, and the patient is still followed 3years later without any recurrence.

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