Abstract

Cryopreservation of peripheral blood hematopoietic stem cells (PBHSC) occurs frequently in the setting of autologous stem cell transplantation. The long-term viability of these cells is an important issue as these patients may eventually experience disease relapse. Previous reports have demonstrated that cryopreserved PBHSCs can retain viability for up to 15 years. We describe the effects of long-term cryopreservation on progenitor viability and activity at our institution.

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